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Article

Deciphering the complexities of human diseases and disorders by coupling induced-pluripotent stem cells and systems genetics.

Wiley interdisciplinary reviews. Systems biology and medicine - 1 Jan 2000

Chang Wing Y, Garcha Kamal, Manias Janet L, Stanford William L

Abstract excerpt

The recent discovery that adult mouse and human somatic cells can be 'reprogrammed' to a state of pluripotency by ectopic expression of only a few transcription factors has already made a major impact on the biomedical community. For the first time, it is possible to study diseases on an individual patient basis, which may eventually lead to the realization of personalized medicine. The utility of...

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PMID: 22492636
DOI: 10.1002/wsbm.1170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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