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Article

The effect of metformin on the efficacy of antiviral therapy in patients with genotype 1 chronic hepatitis C and insulin resistance.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Jun 2012

Yu Jian-Wu, Sun Li-Jie, Zhao Yong-Hua, Kang Peng, Yan Bing-Zhu

Abstract excerpt

OBJECTIVES: Insulin resistance (IR) affects sustained virological response (SVR) in chronic hepatitis C (CHC). The aim of this study was to investigate the effect of adding metformin to peginterferon alfa-2a and ribavirin on the efficacy in patients with genotype 1 CHC and IR. METHODS: Ninety-eight patients with genotype 1 CHC and IR were randomized into the treatment group (n=49) and the control group (n=49)....

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Identifiers

PMID: 22486858
DOI: 10.1016/j.ijid.2012.02.004

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