Article
Selective forces shaping diversity in the class I region of the major histocompatibility complex in dairy cattle.
Animal genetics - 1 Jun 2012
Codner G F, Stear M J, Reeve R, Matthews L, Ellis S A
Abstract excerpt
The major histocompatibility complex (MHC) is one of the most diverse regions of the mammalian genome. Diversity in MHC genes is integral to their function in the immune system, and while pathogens play a key role in shaping this diversity, the contribution of other selective forces remains unclear. The controlled breeding of cattle offers an excellent model for the identification and exploration of these forces....
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