Article
The promoter of Rv0560c is induced by salicylate and structurally-related compounds in Mycobacterium tuberculosis.
PloS one - 1 Jan 2012
Schuessler Dorothée L, Parish Tanya
Abstract excerpt
Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), is a major global health threat. During infection, bacteria are believed to encounter adverse conditions such as iron depletion. Mycobacteria synthesize iron-sequestering mycobactins, which are essential for survival in the host, via the intermediate salicylate. Salicylate is a ubiquitous compound which is known to induce a mild antibiotic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
