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Article

Rv2190c, an NlpC/P60 family protein, is required for full virulence of Mycobacterium tuberculosis.

PloS one - 1 Jan 2012

Parthasarathy Geetha, Lun Shichun, Guo Haidan, Ammerman Nicole C, Geiman Deborah E, Bishai William R

Abstract excerpt

Mycobacterium tuberculosis, the etiologic agent of tuberculosis (TB) possesses at least five genes predicted to encode proteins with NlpC/P60 hydrolase domains, including the relatively uncharacterized Rv2190c. As NlpC/P60 domain-containing proteins are associated with diverse roles in bacterial physiology, our objective was to characterize Rv2190c in M. tuberculosis growth and virulence. Our data indicate that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22952680
DOI: 10.1371/journal.pone.0043429
PMCID: PMC3432046

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