Article
Association of polymorphisms in non-classic MHC genes with susceptibility to autoimmune hepatitis.
Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Apr 2012
Tang Jie, Zhou Cheng, Zhang Zhi-Jun, Zheng Shu-Sen
Abstract excerpt
BACKGROUND: Autoimmune hepatitis is a chronic, generally progressive inflammatory disorder of the liver, of which the cause is unclear. It was demonstrated that genetic factors are involved in its pathogenesis. Previous studies showed that human leukocyte antigen in the major histocompatibility complex (MHC) is associated with susceptibility to autoimmune hepatitis. Current genome scanning studies suggest that...
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