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Article

Matricellular Proteins: A Sticky Affair with Cancers

1 Jan 2012

Abstract excerpt

The multistep process of metastasis is a major hallmark of cancer progression involving the cointeraction and coevolution of the tumor and its microenvironment. In the tumor microenvironment, tumor cells and the surrounding stromal cells aberrantly secrete matricellular proteins, which are a family of nonstructural proteins in the extracellular matrix (ECM) that exert regulatory roles via a variety of molecular...

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Identifiers

PMID: 22481923
DOI: 10.1155/2012/351089

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