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Article

A mRNA signal for the type III secretion of Yop proteins by Yersinia enterocolitica.

Science (New York, N.Y.) - 7 Nov 1997

Anderson D M, Schneewind O

Abstract excerpt

Pathogenic Yersinia species have a specialized secretion system (type III) to target cytotoxic Yop proteins during infection. The signals of YopE and YopN sufficient for the secretion of translational reporter fusions were mapped to the first 15 codons. No common amino acid or peptide sequence could be identified among the secretion signals. Systematic mutagenesis of the secretion signal yielded mutants defective...

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Identifiers

PMID: 9353199
DOI: 10.1126/science.278.5340.1140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A mRNA signal for the type III secretion of Yop proteins by Yersinia enterocolitica.PMID 9353199Read ↗

Yersinia enterocolitica type III secretion: an mRNA signal that couples translation and secretion of YopQ.Semantic proximity Read ↗

Yersinia YopE is targeted for type III secretion by N-terminal, not mRNA, signals.Semantic proximity Read ↗

A synonymous mutation in Yersinia enterocolitica yopE affects the function of the YopE type III secretion signal.Semantic proximity Read ↗

Regulated secretion of YopN by the type III machinery of Yersinia enterocolitica.Semantic proximity Read ↗

Status of YopM and YopN in the Yersinia Yop virulon: YopM of Y.enterocolitica is internalized inside the cytosol of PU5-1.8 macrophages by the YopB, D, N delivery apparatus.Semantic proximity Read ↗

An amino-terminal secretion signal is required for YplA export by the Ysa, Ysc, and flagellar type III secretion systems of Yersinia enterocolitica biovar 1B.Semantic proximity Read ↗

Molecular characterization of type III secretion signals via analysis of synthetic N-terminal amino acid sequences.Semantic proximity Read ↗

Individual chaperones required for Yop secretion by Yersinia.Semantic proximity Read ↗

Impassable YscP substrates and their impact on the Yersinia enterocolitica type III secretion pathway.Semantic proximity Read ↗

Yersinia enterocolitica type III secretion of YopR requires a structure in its mRNA.Semantic proximity Read ↗

Identification of SycN, YscX, and YscY, three new elements of the Yersinia yop virulon.Semantic proximity Read ↗

YopD and LcrH regulate expression of Yersinia enterocolitica YopQ by a posttranscriptional mechanism and bind to yopQ RNA.Semantic proximity Read ↗

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