Article
Yersinia has a tropism for B and T cell zones of lymph nodes that is independent of the type III secretion system.
PLoS pathogens - 1 Sept 2006
Balada-Llasat Joan-Miquel, Mecsas Joan
Abstract excerpt
Pathogenic Yersinia have a pronounced tropism for lymphatic tissues and harbor a virulence plasmid that encodes a type III secretion system, pTTSS, that transports Yops into host cells. Yops are critical virulence factors that prevent phagocytosis by macrophages and neutrophils and Yersinia mutants lacking one or more Yops are defective for survival in lymphatic tissues, liver, and gastrointestinal tract....
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