Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of inflammatory pathway genetic variation on maternal metabolic phenotypes during pregnancy.

PloS one - 1 Jan 2012

Urbanek Margrit, Hayes M Geoffrey, Lee Hoon, Freathy Rachel M, Lowe Lynn P, Ackerman Christine, Jafari Nadereh, Dyer Alan R, Cox Nancy J, Dunger David B, Hattersley Andrew T, Metzger Boyd E, Lowe William L

Abstract excerpt

BACKGROUND: Since mediators of inflammation are associated with insulin resistance, and the risk of developing diabetes mellitus and gestational diabetes, we hypothesized that genetic variation in members of the inflammatory gene pathway impact glucose levels and related phenotypes in pregnancy....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to C-Peptide
Share to Fasting
Share to Hyperglycemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pregnancy Complications

Share to Pregnancy Outcome

Share to Receptors, Adiponectin

Share to Receptors, Leptin

Share to Resistin

Source

Open in PubMed Open full text

Identifiers

PMID: 22479352
DOI: 10.1371/journal.pone.0032958
PMCID: PMC3316547

Genes

ADIPOR2
LEPR
RETN
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22479352-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of inflammatory pathway genetic variation on maternal metabolic phenotypes during pregnancy.PMID 22479352Read ↗

Genetics of glucose homeostasis in pregnancy and postpartum.Semantic proximity Read ↗

Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study: common genetic variants in GCK and TCF7L2 are associated with fasting and postchallenge glucose levels in pregnancy and with the new consensus definition of gestational diabetes mellitus from the International Association of Diabetes and Pregnancy Study Groups.Semantic proximity Read ↗

Metabolomic and genetic associations with insulin resistance in pregnancy.Semantic proximity Read ↗

Polymorphisms in the inflammatory pathway genes and the risk of preeclampsia in Sinhalese women.Semantic proximity Read ↗

Association of maternal and fetal LEPR common variants with maternal glycemic traits during pregnancy.Semantic proximity Read ↗

Ethnic-specific oral glucose tolerance (OGTT) phenotypes in women with hyperglycemia in pregnancy.Semantic proximity Read ↗

The inflammatory gene pathway is not a major contributor to polycystic ovary snydrome.Semantic proximity Read ↗

The role of the polycystic ovary syndrome susceptibility locus D19S884 allele 8 in maternal glycemia and fetal size.Semantic proximity Read ↗

Effects of maternal and fetal LEP common variants on maternal glycemic traits in pregnancy.Semantic proximity Read ↗

Maternal iNOS genetic polymorphisms and hypertensive disorders of pregnancy.Semantic proximity Read ↗

Adrenomedullin signaling pathway polymorphisms and adverse pregnancy outcomes.Semantic proximity Read ↗

Inflammatory mediators gene polymorphisms in preeclampsia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.