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Article

Effects of maternal and fetal LEP common variants on maternal glycemic traits in pregnancy.

Scientific reports - 18 Dec 2017

Lin Rong, Ju Hongfang, Yuan Ziyu, Zhang Caicai, Zeng Liangliang, Sun Yuantian, Su Zhenyu, Jin Li

Abstract excerpt

Previous studies suggest that leptin (LEP) has an important role in glucose metabolism in the nonpregnant state. During pregnancy, circulating maternal concentrations of leptin rise significantly, mainly due to increased secretion of leptin from maternal adipose tissue and placenta. This study aimed to analyze the impact of maternal and fetal common LEP variants on glucose homeostasis in the pregnant state....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29255202
DOI: 10.1038/s41598-017-18117-z
PMCID: PMC5735190

Genes

LEP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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