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Article

Impact of IL6 and IL10 Genotype on Cytokines and Preeclampsia in a Pregnant Multi-Ethnic Cohort of Women With Overweight and Obesity.

Biological research for nursing - 1 Oct 2026

Woo Jennifer, Pearce Michelle, Hulla Ryan, Conley Yvette P, Jancsura McKenzie K

Abstract excerpt

IntroductionAn imbalance between pro- and anti-inflammatory factors is implicated in the pathogenesis of preeclampsia (PE). Although IL10 (rs1800896) and IL6 (rs1800795) genotypes are known to influence circulating cytokine levels, their associations with longitudinal inflammatory profiles across pregnancy have not been well characterized.MethodsWe conducted a retrospective case-control study to longitudinally...

Read the complete abstract on PubMed

Topics

Humans

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Female

Pregnancy

Interleukin-10

Pre-Eclampsia

Interleukin-6

Genotype

Obesity

Adult

Case-Control Studies

Retrospective Studies

Cytokines

Overweight

Cohort Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 42060858
DOI: 10.1177/10998004261445879
PMCID: PMC13558983

Genes

IL10
IL6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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