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Article

Temporal analysis of pathogenic events in virulent and avirulent Brucella melitensis infections.

Cellular microbiology - 1 Oct 2005

Rajashekara Gireesh, Glover David A, Krepps Michael, Splitter Gary A

Abstract excerpt

Despite progress in mouse models of brucellosis, much remains unknown regarding Brucella dissemination and tissue localization. Here, we report the dynamics of Brucella infection in individual mice using bioluminescent Brucella melitensis. Bioluminescent imaging of infected interferon regulatory factor-1 knockout (IRF-1(-/-)) mice identified acute infection in many tissues. Brucella was found to replicate in the...

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PMID: 16153245
DOI: 10.1111/j.1462-5822.2005.00570.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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