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Article

Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell line

4 Apr 2012

Abstract excerpt

BACKGROUND: Osteosarcoma is a bone-forming tumor of mesenchymal origin that presents a clinical pattern that is consistent with the cancer stem cell model. Cells with stem-like properties (CSCs) have been identified in several tumors and hypothesized as the responsible for the relative resistance to therapy and tumor relapses. In this study, we aimed to identify and characterize CSCs populations in a human...

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PMID: 22475227
DOI: 10.1186/1471-2407-12-139

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