Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

P-selectin genotype is associated with the development of cancer cachexia.

EMBO molecular medicine - 1 Jun 2012

Tan Benjamin H L, Fladvad Torill, Braun Theodore P, Vigano Antonio, Strasser Florian, Deans D A Christopher, Skipworth Richard J E, Solheim Tora S, Damaraju Sambasivarao, Ross James A, Kaasa Stein, Marks Daniel L, Baracos Vickie E, Skorpen Frank, Fearon Kenneth C H

Abstract excerpt

The variable predisposition to cachexia may, in part, be due to the interaction of host genotype. We analyzed 129 single nucleotide polymorphisms (SNPs) in 80 genes for association with cachexia based on degree of weight loss (>5, >10, >15%) as well as weight loss in the presence of systemic infl...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to C-Reactive Protein
Share to Cachexia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Disease Models, Animal

Share to Neoplasms

Share to P-Selectin

Share to Weight Loss

Source

Open in PubMed Open full text

Identifiers

PMID: 22473907
DOI: 10.1002/emmm.201200231
PMCID: PMC3443952

Genes

SELP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22473907-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

P-selectin genotype is associated with the development of cancer cachexia.PMID 22473907Read ↗

Genetic basis of interindividual susceptibility to cancer cachexia: selection of potential candidate gene polymorphisms for association studies.Semantic proximity Read ↗

Identification of possible genetic polymorphisms involved in cancer cachexia: a systematic review.Semantic proximity Read ↗

New genetic signatures associated with cancer cachexia as defined by low skeletal muscle index and weight loss.Semantic proximity Read ↗

Association of the rs3917647 polymorphism of the SELP gene with malnutrition in gastric cancer.Semantic proximity Read ↗

E-selectin S128R polymorphism is associated with cancer risk: a meta-analysis.Semantic proximity Read ↗

AKT1 and SELP Polymorphisms Predict the Risk of Developing Cachexia in Pancreatic Cancer PatientsSemantic proximity Read ↗

Cytokine gene polymorphisms and susceptibility to cachexia.Semantic proximity Read ↗

Biomarkers for cancer cachexia: is there also a genetic component to cachexia?Semantic proximity Read ↗

Cancer cachexia is associated with the IL10 -1082 gene promoter polymorphism in patients with gastroesophageal malignancy.Semantic proximity Read ↗

Bioinformatics Analyzes of Selectins Polymorphisms Reveal New Potential Cancer BiomarkersSemantic proximity Read ↗

ACVR2B polymorphism, Adiponectin, and GDF-15 levels as biomarkers for cachexia in gastrointestinal cancer.Semantic proximity Read ↗

Analysis of E-Selectin S128R gene polymorphism in pancreatic cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.