Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ACVR2B polymorphism, Adiponectin, and GDF-15 levels as biomarkers for cachexia in gastrointestinal cancer.

Scientific reports - 12 Nov 2024

de Martin Coletti Laura, Segura Gabriela Gonzalez, de Freitas Leticia Cangemi Guedes, de Souza Rangel Machado Jackeline, Beleboni Rene, Faccio Adilson, Marins Mozart, Fachin Ana Lúcia

Abstract excerpt

Reversing cancer cachexia remains a challenge. Genetic biomarkers for the early detection of the disease have been explored in order to enable the implementation of preventive measures. We therefore genotyped candidate genes based on cachexia phenotype and quantified adiponectin and GDF-15 levels in cachectic patients with gastrointestinal cancer. Patients with a diagnosis of gastrointestinal cancer were divided...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Activin Receptors, Type II
Share to Adiponectin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to Cachexia

Share to Case-Control Studies

Share to Gastrointestinal Neoplasms

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 39533028
DOI: 10.1038/s41598-024-79176-7
PMCID: PMC11557708

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ACVR2B polymorphism, Adiponectin, and GDF-15 levels as biomarkers for cachexia in gastrointestinal cancer.PMID 39533028Read ↗

New genetic signatures associated with cancer cachexia as defined by low skeletal muscle index and weight loss.Semantic proximity Read ↗

Identification of possible genetic polymorphisms involved in cancer cachexia: a systematic review.Semantic proximity Read ↗

A genome wide association study to identify germline variants associated with cancer-associated cachexia - a preliminary analysisSemantic proximity Read ↗

Biomarkers for cancer cachexia: is there also a genetic component to cachexia?Semantic proximity Read ↗

Specific miRNAs are associated with human cancer cachexia in an organ‐specific mannerSemantic proximity Read ↗

IRX1 Promotes Loss of Subcutaneous Adipose Tissue by Inhibiting Adipocyte Differentiation in Cachectic Patients with Gastric CancerSemantic proximity Read ↗

AKT1 and SELP Polymorphisms Predict the Risk of Developing Cachexia in Pancreatic Cancer PatientsSemantic proximity Read ↗

Growth differentiation factor 15 and its role in carcinogenesis: an updateSemantic proximity Read ↗

Identification of Bone Morphogenetic Protein 7 as a Master Regulator of Gastric Cancer-Associated CachexiaSemantic proximity Read ↗

Genetic basis of interindividual susceptibility to cancer cachexia: selection of potential candidate gene polymorphisms for association studies.Semantic proximity Read ↗

Evaluation of GDF15 as a therapeutic target of cardiometabolic diseases in human: A Mendelian randomization studySemantic proximity Read ↗

C-reactive protein levels and vitamin d receptor polymorphisms as markers in predicting cachectic syndrome in cancer patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.