Article
A common genetic variant of FCN3/CD164L2 is associated with essential hypertension in a Chinese population.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2012
Lu Jingyi, Li Ming, Zhang Rong, Hu Cheng, Wang Congrong, Jiang Feng, Yu Weihui, Qin Wen, Tang Shanshan, Jia Weiping
Abstract excerpt
Ficolin-3, encoded by FCN3, is the predominant recognition molecule of lectin pathway for the activation of complement component 3 (C3), which is an important risk factor for the development of hypertension. In our previous study, we found the complement system including ficolin-3 was overrepresented in the serum of type 2 diabetic patients. Since type 2 diabetes shares some pathogenic components, including...
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