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Article

Three different KRAS statuses in three synchronous colorectal cancers.

Medical oncology (Northwood, London, England) - 1 Dec 2012

Jolissaint L, Cacheux W, Mariani P, Le Tourneau C, Lièvre A, Lappartient E, Margogne A, Farkhondeh F, de Cremoux P

Abstract excerpt

Treatments with monoclonal antibodies targeting the epidermal growth factor receptors (EGFR) have improved the prognosis of metastatic colorectal cancer (CRC). Mutated KRAS status is predictive of resistance to anti-EGFR agents and allows the selection of KRAS wild-type patients who may benefit from these targeted therapies. We report an original case of metastatic CRC including three synchronous primary tumors...

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Source

Identifiers

PMID: 22467075
DOI: 10.1007/s12032-012-0214-z

Genes

KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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