Article
Platelet glycoprotein IIIA PIA2 polymorphism is associated with ST elevation acute myocardial infarction in young Mexican population.
Journal of thrombosis and thrombolysis - 1 May 2012
Santiago-Germán David, Leaños-Miranda Alfredo, García-Latorre Ethel, Borrayo-Sánchez Gabriela, Majluf-Cruz Abraham, Isordia-Salas Irma
Abstract excerpt
Platelet membrane glycoprotein IIb/IIIa plays an important role in adhesion and platelet aggregation. Polymorphisms of genes in platelet activation and fibrinolysis have been associated with myocardial infarction (MI), however this has not been confirmed by others, and results are still controversial. The aim of this study was to determine the frequency distribution and association of polymorphism in the platelet...
Topics
- Adult
- Alleles
- Female
- Gene Frequency
- Humans
- Integrin beta3
- Male
- Mexico
- Middle Aged
- Myocardial Infarction
- Platelet Glycoprotein GPIIb-IIIa Complex
- Polymorphism, Genetic
- Risk Factors