Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Social disorder, APOE-E4 genotype, and change in cognitive function among older adults living in Chicago.

Social science & medicine (1982) - 1 May 2012

Boardman Jason D, Barnes Lisa L, Wilson Robert S, Evans Denis A, Mendes de Leon Carlos F

Abstract excerpt

The goal of this paper is to describe the simultaneous influence of social and genetic risk factors on declines in cognitive functioning among older American adults. We use detailed information about the social characteristics of older adults' neighborhoods from the Chicago Health and Aging Project (n = 1655; ages 65+) in conjunction with information about respondent's APOE genotype to predict changes in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein E4
Share to Chicago
Share to Cognition Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Educational Status

Share to Longitudinal Studies

Share to Residence Characteristics

Share to Social Environment

Share to Stress, Psychological

Source

Open in PubMed Open full text

Identifiers

PMID: 22465377
DOI: 10.1016/j.socscimed.2012.02.012
PMCID: PMC3597347

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Social disorder, APOE-E4 genotype, and change in cognitive function among older adults living in Chicago.PMID 22465377Read ↗

Neighborhood psychosocial environment, apolipoprotein E genotype, and cognitive function in older adults.Semantic proximity Read ↗

Social Environment, Lifestyle, and Genetic Predisposition With Dementia Risk: A Long-Term Longitudinal Study Among Older Adults.Semantic proximity Read ↗

Differential moderation effects of ApoE and 5-HTTLPR genotypes on social vulnerability in predicting mortality among community-dwelling middle-aged and older adults: a nationwide population-based study.Semantic proximity Read ↗

Impact of the Apolipoprotein E ε4 Allele on the Relationship Between Healthy Lifestyle and Cognitive Decline: A Population-Based Study.Semantic proximity Read ↗

Race, APOE genotypes, and cognitive decline among middle-aged urban adults.Semantic proximity Read ↗

Childhood socioeconomic status and genetic risk for poorer cognition in later life.Semantic proximity Read ↗

A multilevel analysis of the influence of Apolipoprotein E genotypes on depressive symptoms in late-life moderated by the environment.Semantic proximity Read ↗

Apolipoprotein e genotype, cortisol, and cognitive function in community-dwelling older adults.Semantic proximity Read ↗

Unequal expression: Social position modulates APOE genotype risk of dementia.Semantic proximity Read ↗

Social support may buffer the effect of APOE ε4 allele on cognition in older adults.Semantic proximity Read ↗

Race and Apolipoprotein E-e4 Allele Status Differences in the Association Between Loneliness and Cognitive Decline.Semantic proximity Read ↗

Gene-environment interaction of body mass index and apolipoprotein E ε4 allele on cognitive decline.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.