Nucleosome organization affects the sensitivity of gene expression to promoter mutations.

Abstract excerpt

Gene expression diverges rapidly between related species, playing a key role in the evolution of new phenotypes. The extent of divergence differs greatly between genes and is correlated to promoter nucleosome organization. We hypothesized that this may be partially explained by differential sensitivity of expression to mutations in the promoter region. We measured the sensitivity of 22 yeast promoters with...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Binding Sites
• Share to Gene Expression
• Share to Gene Expression Regulation