Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disrupted small-world brain networks in moderate Alzheimer's disease: a resting-state FMRI study.

PloS one - 1 Jan 2012

Zhao Xiaohu, Liu Yong, Wang Xiangbin, Liu Bing, Xi Qian, Guo Qihao, Jiang Hong, Jiang Tianzi, Wang Peijun

Abstract excerpt

The small-world organization has been hypothesized to reflect a balance between local processing and global integration in the human brain. Previous multimodal imaging studies have consistently demonstrated that the topological architecture of the brain network is disrupted in Alzheimer's disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alzheimer Disease
Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Genotype

Share to Magnetic Resonance Imaging

Source

Open in PubMed Open full text

Identifiers

PMID: 22457774
DOI: 10.1371/journal.pone.0033540
PMCID: PMC3311642

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22457774-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disrupted small-world brain networks in moderate Alzheimer's disease: a resting-state FMRI study.PMID 22457774Read ↗

Disrupted functional and structural networks in cognitively normal elderly subjects with the APOE ɛ4 allele.Semantic proximity Read ↗

A Whole-Brain Computational Modeling Approach to Explain the Alterations in Resting-State Functional Connectivity during Progression of Alzheimer’s DiseaseSemantic proximity Read ↗

Apolipoprotein E allele 4 effects on Single-Subject Gray Matter Networks in Mild Cognitive Impairment.Semantic proximity Read ↗

From Resilience to Collapse: Review on Brain topology in Early Onset DementiaSemantic proximity Read ↗

Functional brain network controllability dysfunction in Alzheimer’s disease and its relationship with cognition and gene expression profilingSemantic proximity Read ↗

A FDG-PET Study of Metabolic Networks in Apolipoprotein E ε4 Allele Carriers.Semantic proximity Read ↗

Loss of functional connectivity is greater outside the default mode network in nonfamilial early-onset Alzheimer's disease variants.Semantic proximity Read ↗

Altered small-world anatomical networks in Apolipoprotein-E4 (ApoE4) carriers using MRI.Semantic proximity Read ↗

FMRI Functional Connectivity Evaluation in Alzheimer’s Stages: Linear and Non-Linear ApproachesSemantic proximity Read ↗

Alterations in topological and dynamical parameters correlate with disease biomarkers and neuropsychological scores in prodromic stages of dementiaSemantic proximity Read ↗

Altered dynamic brain functional connectivity in patients with white matter hyperintensities: a prospective case-control studySemantic proximity Read ↗

Default mode network activity and white matter integrity in healthy middle-aged ApoE4 carriers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.