Article
Mutual repression by bantam miRNA and Capicua links the EGFR/MAPK and Hippo pathways in growth control.
Current biology : CB - 24 Apr 2012
Herranz Héctor, Hong Xin, Cohen Stephen M
Abstract excerpt
BACKGROUND: The epidermal growth factor receptor (EGFR) and Hippo signaling pathways control cell proliferation and apoptosis to promote tissue growth during development. Misregulation of these pathways is implicated in cancer. Our understanding of the mechanisms that integrate the activity of these pathways remains fragmentary. This study identifies bantam microRNA as a common target of these pathways and...
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