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Article

The effect of bambuterol (carbamylated terbutaline) on plasma cholinesterase activity and suxamethonium-induced neuromuscular blockade in genotypically normal patients.

Acta anaesthesiologica Scandinavica - 1 Oct 1990

Bang U, Viby-Mogensen J, Wirén J E, Skovgaard L T

Abstract excerpt

Bambuterol (the bisdimethylcarbamate prodrug of terbutaline) is a new bronchodilator with a prolonged duration of action due to its inhibition of plasma cholinesterase during metabolism. The effect of bambuterol on suxamethonium-induced neuromuscular blockade was studied in 10 patients undergoing elective laparotomy. Thirty mg of bambuterol was given 2 h before anaesthesia, which was performed with thiopentone,...

Topics

Adult
Aged
Anesthesia, Inhalation
Bronchodilator Agents
Cholinesterases
Depression, Chemical
Female
Genotype
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neuromuscular Junction

Succinylcholine

Terbutaline

Time Factors

Source

Identifiers

PMID: 2244449
DOI: 10.1111/j.1399-6576.1990.tb03152.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2244449-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The effect of bambuterol (carbamylated terbutaline) on plasma cholinesterase activity and suxamethonium-induced neuromuscular blockade in genotypically normal patients.PMID 2244449Read ↗

The effect of bambuterol on plasma cholinesterase activity and suxamethonium-induced neuromuscular blockade in subjects heterozygous for abnormal plasma cholinesterase.Semantic proximity Read ↗

Clinical importance of plasma cholinesterase for the anaesthetist.Semantic proximity Read ↗

Interaction of human butyrylcholinesterase variants with bambuterol and terbutaline.Semantic proximity Read ↗

Interactions of bambuterol with human serum cholinesterase of the genotypes EuEu (normal), EaEa (atypical) and EuEa.Semantic proximity Read ↗

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Pharmacokinetics of bambuterol in subjects homozygous for the atypical gene for plasma cholinesterase.Semantic proximity Read ↗

Cholinesterase unit establishment and issuing of >>Warning Cards<< for carriers of suxamethonium sensitive serum butyrylcholinesterase variants.Semantic proximity Read ↗

Influence of plasma cholinesterase activity on recovery from mivacurium-induced neuromuscular blockade in phenotypically normal patients.Semantic proximity Read ↗

Prolonged neuromuscular block associated with mivacurium.Semantic proximity Read ↗

Edrophonium requirements for reversal of deep neuromuscular block following infusion of mivacurium.Semantic proximity Read ↗

Use of neuromuscular monitoring to detect prolonged effect of succinylcholine or mivacurium: three case reports.Semantic proximity Read ↗

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