Article
Transient receptor potential genes, smoking, occupational exposures and cough in adults.
Respiratory research - 23 Mar 2012
Smit Lidwien A M, Kogevinas Manolis, Antó Josep M, Bouzigon Emmanuelle, González Juan Ramón, Le Moual Nicole, Kromhout Hans, Carsin Anne-Elie, Pin Isabelle, Jarvis Deborah, Vermeulen Roel, Janson Christer, Heinrich Joachim, Gut Ivo, Lathrop Mark, Valverde Miguel A, Demenais Florence, Kauffmann Francine
Abstract excerpt
BACKGROUND: Transient receptor potential (TRP) vanilloid and ankyrin cation channels are activated by various noxious chemicals and may play an important role in the pathogenesis of cough. The aim was to study the influence of single nucleotide polymorphisms (SNPs) in TRP genes and irritant exposures on cough. METHODS: Nocturnal, usual, and chronic cough, smoking, and job history were obtained by questionnaire in...
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