Article
Update on antiglomerular basement membrane disease.
Current opinion in rheumatology - 1 Jan 2011
Peto Philippa, Salama Alan D
Abstract excerpt
PURPOSE OF REVIEW: Antiglomerular basement membrane (GBM) disease is a rare form of autoimmune glomerulonephritis often accompanied by lung haemorrhage and characterized by circulating and deposited antibodies that bind basement membrane type IV collagen antigens in the glomerulus and lung alveolus. We review recent findings regarding disease pathogenesis and therapy. RECENT FINDINGS: The target autoantigens are...
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