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Article

Advanced glycation end products induce a prothrombotic phenotype in mice via interaction with platelet CD36.

Blood - 21 Jun 2012

Zhu Weifei, Li Wei, Silverstein Roy L

Abstract excerpt

Diabetes mellitus has been associated with platelet hyperreactivity, which plays a central role in the hyperglycemia-related prothrombotic phenotype. The mechanisms responsible for this phenomenon are not established. In the present study, we investigated the role of CD36, a class-B scavenger receptor, in this process. Using both in vitro and in vivo mouse models, we demonstrated direct and specific interactions...

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Share to Asymptomatic Diseases
Share to CD36 Antigens
Share to Diabetes Mellitus, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Diet, Atherogenic

Share to Glycation End Products, Advanced

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Source

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Identifiers

PMID: 22431576
DOI: 10.1182/blood-2011-10-387506
PMCID: PMC3383021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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