Article
Association of myeloperoxidase polymorphism (G463A) with cervix cancer.
Molecular and cellular biochemistry - 1 Jun 2015
Castelão Cindy, da Silva Alda Pereira, Matos Andreia, Inácio Ângela, Bicho Manuel, Medeiros Rui, Bicho Maria Clara
Abstract excerpt
Cervical cancer is the fourth most common cancer affecting women worldwide, according to the latest IARC release with 528 000 new cases every year. Infection by high-risk human papillomavirus (HPV) is necessary but not sufficient for progression to cancer. Epithelial tissues, the target of HPV infection, are heavily exposed to reactive oxygen species (ROS). Hypochlorous acid (HOCl) is a very potent ROS, and it is...
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