Article
The Drosophila protein mustard tailors the innate immune response activated by the immune deficiency pathway.
Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2012
Wang Zhipeng, Berkey Cristin D, Watnick Paula I
Abstract excerpt
In this study, we describe a Drosophila melanogaster transposon insertion mutant with tolerance to Vibrio cholerae infection and markedly decreased transcription of diptericin as well as other genes regulated by the immune deficiency innate immunity signaling pathway. We present genetic evidence that this insertion affects a locus previously implicated in pupal eclosion. This genetic locus, which we have named...
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