Article
Genetic analysis of Drosophila melanogaster susceptibility to intestinal Vibrio cholerae infection.
Cellular microbiology - 1 Mar 2009
Berkey Cristin D, Blow Nathan, Watnick Paula I
Abstract excerpt
We previously demonstrated that Vibrio cholerae is able to colonize the intestine of the fly to produce a lethal infection. Here we present the results of a genetic screen undertaken to identify factors that alter susceptibility of the fly to intestinal V. cholerae infection. In this model of infection, the Eiger/Wengen signalling pathway protects the fly against infection. Furthermore, mutations within the IMD...
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