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Article

FMR1 low sub-genotype does not rescue BRCA1/2-mutated human embryos and does not explain primary ovarian insufficiency among BRCA1/2-carriers.

Human reproduction (Oxford, England) - 1 Aug 2013

Brandão R D, van Roozendaal K, Tserpelis D, Blok M J

Abstract excerpt

STUDY QUESTION: Can we confirm in our population whether FMRI low sub-genotypes are associated with BRCA1/2 mutations, as recently proposed? SUMMARY ANSWER: Our results indicate that the distribution of the FMR1 sub-genotypes in female BRCA1/2-mutation carriers is significantly different from what has been reported previously and resembles that of the control population. FMRI low sub-genotypes are not associated...

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Share to Embryo, Mammalian
Share to Fragile X Mental Retardation Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA1

Share to Genes, BRCA2

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Share to Heterozygote

Share to Preimplantation Diagnosis

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Source

Identifiers

PMID: 23760159
DOI: 10.1093/humrep/det254

Genes

BRCA1
FMR1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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