Article
Extinction and fixation times with dominance and inbreeding.
Theoretical population biology - 1 Jun 2012
Glémin Sylvain
Abstract excerpt
The effect of partial inbreeding on extinction and fixation times of a selected allele with partial dominance is studied using a diffusion model. Asymptotic approximations are obtained for large populations and the accuracy of the approximations was found to increase with inbreeding level. They show that inbreeding reduces extinction and fixation times compared to random mating at least by a factor 1+F, where F...
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