Article
Influence of selection on the probability of fixation at a locus with multiple alleles.
BMC genomics - 30 Aug 2024
Overall A D J, Waxman D
Abstract excerpt
BACKGROUND: Genes exist in a population in a variety of forms (alleles), as a consequence of multiple mutation events that have arisen over the course of time. In this work we consider a locus that is subject to either multiplicative or additive selection, and has n alleles, where n can take the values 2, 3, 4, … . We focus on determining the probability of fixation of each of the n alleles. For n = 2 alleles,...
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