Effects of dominance on the probability of fixation of a mutant allele.

Abstract excerpt

We consider whether the fixation probability of an allele in a two-allele diploid system is always a monotonic function of the selective advantage of the allele. We show that while this conjecture is correct for intermediate dominance, it is not correct in general for either overdominant or underdominant alleles, and that for some parameter ranges the fixation probability can initially decrease and then increase...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Heterozygote
• Share to Algorithms
• Share to Diploidy