Article
Inbreeding load in finite populations from dominant and overdominant mutations.
Proceedings. Biological sciences - 1 Jul 2025
González-Castellano Inés, García-Dorado Aurora, Caballero Armando
Abstract excerpt
Inbreeding depression is a widespread phenomenon that reflects the burden of deleterious effects hidden in heterozygosis in non-inbred populations but exposed in homozygosis in inbred individuals, known as inbreeding load (B). This load can be due to partially or fully recessive deleterious mutations (dominance model) or to heterozygote advantage (overdominance model, where both homozygotes are deleterious...
Read the complete abstract on PubMedTopics
- Inbreeding
- Mutation
- Models, Genetic
- Computer Simulation
- Inbreeding Depression
- Animals
- Genes, Dominant
