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Article

Predicting the lethal phenotype of the knockout mouse by integrating comprehensive genomic data.

Bioinformatics (Oxford, England) - 1 May 2012

Yuan Yuan, Xu Yanxun, Xu Jianfeng, Ball Robyn L, Liang Han

Abstract excerpt

MOTIVATION: The phenotypes of knockout mice provide crucial information for understanding the biological functions of mammalian genes. Among various knockout phenotypes, lethality is of great interest because those involved genes play essential roles. With the availability of large-scale genomic data, we aimed to assess how well the integration of various genomic features can predict the lethal phenotype of...

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Identifiers

PMID: 22419784
DOI: 10.1093/bioinformatics/bts120
PMCID: PMC3338016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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