Article

TSUMUGI: a platform for phenotype-driven gene network identification from comprehensive knockout mouse phenotyping data

2026-02-19

Abstract excerpt

<h4>Summary</h4> Deciphering complex organismal phenotypes requires elucidation of coordinated functions among multiple genes, yet this remains a fundamental challenge in functional genetics. The International Mouse Phenotyping Consortium (IMPC) has recently established a comprehensive phenotypic atlas based on systematic single-gene knockout mouse lines, providing an unprecedented resource for gene-phenotype ass...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fab2bd38-09c0-59ce-8212-f02af32678a4
DOI: 10.64898/2026.02.18.706720

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

TSUMUGI: a platform for phenotype-driven gene network identification from comprehensive knockout mouse phenotyping dataDOI 10.64898/2026.02.18.706720Read

The International Mouse Phenotyping Consortium: comprehensive knockout phenotyping underpinning the study of human disease.Semantic proximity Read

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.Semantic proximity Read

An atlas of evidence-based phenotypic associations across the mouse phenome.Semantic proximity Read

Computational identification of disease models through cross-species phenotype comparison.Semantic proximity Read

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.Semantic proximity Read

Commentary: The International Mouse Phenotyping Consortium: high-throughput in vivo functional annotation of the mammalian genome.Semantic proximity Read

Tissue-specific functional networks for prioritizing phenotype and disease genes.Semantic proximity Read

A gene-phenotype network for the laboratory mouse and its implications for systematic phenotyping.Semantic proximity Read

Investigating gene function and human disease through data on the IMPC portalSemantic proximity Read

Mouse phenome database.Semantic proximity Read

International Mouse Phenotyping Consortium: Investigating gene function and providing insights into human diseaseSemantic proximity Read

The Mammalian Phenotype Ontology as a unifying standard for experimental and high-throughput phenotyping data.Semantic proximity Read