Article
Polymorphisms in cytotoxic T lymphocyte associated antigen-4 influence the rate of acute rejection after renal transplantation in 167 Chinese recipients.
Transplant immunology - 1 Jun 2012
Gao Jun-wei, Guo Yi-feng, Fan Yu, Qiu Jian-xin, Bao Er-dun, Liu Yong, Qin Yan, Zhang Fang
Abstract excerpt
Gene polymorphisms of cytotoxic T lymphocyte associated antigen 4 (CTLA4) play an influential role in the graft rejection and long-term clinical outcome of organ transplantation. We investigated the associations of five CTLA4 single nucleotide polymorphisms (SNPs) (rs733618T/C, rs4553808A/G, rs5742909C/T, rs231775G/A, rs3087243G/A) on the early acute rejection (AR) of Chinese deceased donor renal transplantation...
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