Article
Association between CTLA4 gene polymorphisms and acute rejection of kidney transplantation: a meta-analysis.
Journal of nephrology - 1 Jan 2000
Duan Zhenhua, Zhang Yujing, Pan Faming, Zhang Tianchen, Zeng Zhen, Wang Sheng, Li Guixing, Shen Beibei, Gao Jing
Abstract excerpt
OBJECTIVE: Cytotoxic T-lymphocyte-associated protein 4 (CTLA4) has been shown to transmit an inhibitory signal to T cells, which is a therapeutic target for acute rejection of kidney transplantation, and CTLA4 polymorphisms have also been considered as a potential risk factor. However, major studies have not yielded significant results. Thus, we conducted a meta-analysis of existing studies to boost their...
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