Article
Detecting selective sweeps from pooled next-generation sequencing samples.
Molecular biology and evolution - 1 Sept 2012
Boitard Simon, Schlötterer Christian, Nolte Viola, Pandey Ram Vinay, Futschik Andreas
Abstract excerpt
Due to its cost effectiveness, next-generation sequencing of pools of individuals (Pool-Seq) is becoming a popular strategy for characterizing variation in population samples. Because Pool-Seq provides genome-wide SNP frequency data, it is possible to use them for demographic inference and/or the identification of selective sweeps. Here, we introduce a statistical method that is designed to detect selective...
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