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Article

Overactivation of hedgehog signaling alters development of the ovarian vasculature in mice.

Biology of reproduction - 1 Jun 2012

Ren Yi, Cowan Robert G, Migone Fernando F, Quirk Susan M

Abstract excerpt

The hedgehog (HH) signaling pathway is critical for ovarian function in Drosophila, but its role in the mammalian ovary has not been defined. Previously, expression of a dominant active allele of the HH signal transducer protein smoothened (SMO) in Amhr2(cre/+)SmoM2 mice caused anovulation in ass...

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Identifiers

PMID: 22402963
DOI: 10.1095/biolreprod.112.099176
PMCID: PMC3386146

Genes

SMO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22402963-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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