Article
Activation of sorbitol pathway in metabolic syndrome and increased susceptibility to cataract in Wistar-Obese rats.
Molecular vision - 1 Jan 2012
Reddy Paduru Yadagiri, Giridharan Nappan Veettil, Reddy Geereddy Bhanuprakash
Abstract excerpt
PURPOSE: Obesity is a major public health problem worldwide, and of late, epidemiological studies indicate a preponderance of cataracts under obesity conditions. Although cataract is a multifactorial disorder and various biochemical mechanisms have been proposed, the influence of obesity on cataractogenesis has yet to be investigated. In such a scenario, a suitable animal model that develops cataract following...
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