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Article

Disruption of exploratory and habituation behavior in mice with mutation of DISC1: an ethologically based analysis.

Journal of neuroscience research - 1 Jul 2012

Walsh J, Desbonnet L, Clarke N, Waddington J L, O'Tuathaigh C M P

Abstract excerpt

Disrupted-in-schizophrenia-1 (DISC1) is a gene that has been functionally linked with neurodevelopmental processes and structural plasticity in the brain. Clinical genetic investigations have implicated DISC1 as a genetic risk factor for schizophrenia and related psychoses. Studies using mutant mouse models of DISC1 gene function have demonstrated schizophrenia-related anatomical and behavioral endophenotypes. In...

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Share to Exploratory Behavior
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Habituation, Psychophysiologic

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Source

Identifiers

PMID: 22388794
DOI: 10.1002/jnr.23024

Genes

DISC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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