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Article

Genetic variation in antioxidant enzymes and lung function.

Free radical biology & medicine - 1 May 2012

Bentley Amy R, Kritchevsky Stephen B, Harris Tamara B, Newman Anne B, Bauer Douglas C, Meibohm Bernd, Clark Andrew G, Cassano Patricia A

Abstract excerpt

Not all cigarette smokers develop chronic obstructive pulmonary disease, and discovering susceptibility factors is an important research priority. The oxidative burden of smoking may overwhelm antioxidant defenses, and vulnerabilities may exist as a result of sequence variants in genes encoding antioxidant enzymes. This study explored the association between genetic variation in a network of antioxidant enzymes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22387199
DOI: 10.1016/j.freeradbiomed.2012.02.025
PMCID: PMC3390784

Genes

FEV
IDH2
PRDX5

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