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Article

Structural and functional analysis of validoxylamine A 7'-phosphate synthase ValL involved in validamycin A biosynthesis.

PloS one - 1 Jan 2012

Zheng Lina, Zhou Xiang, Zhang Huaidong, Ji Xiaofeng, Li Lei, Huang Lin, Bai Linquan, Zhang Houjin

Abstract excerpt

Validamycin A (Val-A) is an effective antifungal agent widely used in Asian countries as crop protectant. Validoxylamine A, the core structure and intermediate of Val-A, consists of two C(7)-cyclitol units connected by a rare C-N bond. In the Val-A biosynthetic gene cluster in Streptomyces hygros...

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Identifiers

PMID: 22384130
DOI: 10.1371/journal.pone.0032033
PMCID: PMC3288074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22384130-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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