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Article

A mathematical model of mitotic exit in budding yeast: the role of Polo kinase.

PloS one - 1 Jan 2012

Hancioglu Baris, Tyson John J

Abstract excerpt

Cell cycle progression in eukaryotes is regulated by periodic activation and inactivation of a family of cyclin-dependent kinases (Cdk's). Entry into mitosis requires phosphorylation of many proteins targeted by mitotic Cdk, and exit from mitosis requires proteolysis of mitotic cyclins and dephosphorylation of their targeted proteins. Mitotic exit in budding yeast is known to involve the interplay of mitotic...

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PMID: 22383977
DOI: 10.1371/journal.pone.0030810
PMCID: PMC3285609

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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