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Article

A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associated with combined hyperlipidaemia in obesity.

European journal of endocrinology - 1 Mar 2001

Swarbrick M M, Chapman C M, McQuillan B M, Hung J, Thompson P L, Beilby J P

Abstract excerpt

OBJECTIVE: Peroxisome proliferator-activated receptor-gamma 2 (PPAR gamma 2) is an important regulator of adipose tissue metabolism and insulin sensitivity. The aim of this investigation was to determine whether a PPAR gamma 2 Pro12Ala polymorphism was associated with cardiovascular risk factors...

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Alanine
Anthropometry
Cholesterol, HDL
Diabetes Mellitus
Hyperlipidemias
Proline

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Cytoplasmic and Nuclear

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PMID: 11248748
DOI: 10.1530/eje.0.1440277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-11248748-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associated with combined hyperlipidaemia in obesity.PMID 11248748Read ↗

PPAR-gamma2 Pro12Ala polymorphism in the population of obese and non-obese men of the city of Wroclaw.Semantic proximity Read ↗

Effects of Pro12Ala polymorphism in peroxisome proliferator-activated receptor-γ2 gene on metabolic syndrome risk: a meta-analysis.Semantic proximity Read ↗

The Peroxisome Proliferator-Activated Receptor-γ2 Pro12Ala PolymorphismSemantic proximity Read ↗

Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study.Semantic proximity Read ↗

Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population.Semantic proximity Read ↗

Ala/Ala genotype of Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-γ2 gene is associated with obesity and insulin resistance in Asian Indians.Semantic proximity Read ↗

The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma2 gene is not associated with postprandial responses to glucose or fat tolerance tests in young healthy subjects: the European Atherosclerosis Research Study II.Semantic proximity Read ↗

Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations.Semantic proximity Read ↗

Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma-2 gene on adiposity, insulin sensitivity and lipid profile in the Spanish population.Semantic proximity Read ↗

Polymorphism of Pro12Ala in the peroxisome proliferator-activated receptor gamma2 gene in Iranian diabetic and obese subjects.Semantic proximity Read ↗

Association between PPAR-γ2 Pro12Ala polymorphism and obesity: a meta-analysis.Semantic proximity Read ↗

Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma2 (PPARgamma2) is associated with higher levels of total cholesterol and LDL-cholesterol in male caucasian type 2 diabetes patients.Semantic proximity Read ↗

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