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Article

Pharmacogenetic association of the galanin receptor (GALR1) SNP rs2717162 with smoking cessation.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jun 2012

Gold Allison B, Wileyto E Paul, Lori Adriana, Conti David, Cubells Joseph F, Lerman Caryn

Abstract excerpt

Galanin modulates dopaminergic neurotransmission in the mesolimbic dopamine system, thereby influencing the rewarding effects of nicotine. Variants in the galanin receptor 1 (GALR1) gene have been associated with retrospective craving severity and heaviness of smoking in prior research. We investigated pharmacogenetic associations of the previously studied GALR1 polymorphism, rs2717162, in 1217 smokers of...

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Identifiers

PMID: 22373943
DOI: 10.1038/npp.2012.13
PMCID: PMC3358736

Genes

GALR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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