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Article

Characterization of spontaneous bone marrow recovery after sublethal total body irradiation: importance of the osteoblastic/adipocytic balance.

PloS one - 1 Jan 2012

Poncin Géraldine, Beaulieu Aurore, Humblet Chantal, Thiry Albert, Oda Kimimitsu, Boniver Jacques, Defresne Marie-Paule

Abstract excerpt

Many studies have already examined the hematopoietic recovery after irradiation but paid with very little attention to the bone marrow microenvironment. Nonetheless previous studies in a murine model of reversible radio-induced bone marrow aplasia have shown a significant increase in alkaline phosphatase activity (ALP) prior to hematopoietic regeneration. This increase in ALP activity was not due to cell...

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Identifiers

PMID: 22363493
DOI: 10.1371/journal.pone.0030818
PMCID: PMC3281884

Genes

MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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