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Article

The crystal structure of the FAD/NADPH-binding domain of flavocytochrome P450 BM3.

The FEBS journal - 1 May 2012

Joyce Michael G, Ekanem Idorenyin S, Roitel Olivier, Dunford Adrian J, Neeli Rajasekhar, Girvan Hazel M, Baker George J, Curtis Robin A, Munro Andrew W, Leys David

Abstract excerpt

We report the crystal structure of the FAD/NADPH-binding domain (FAD domain) of the biotechnologically important Bacillus megaterium flavocytochrome P450 BM3, the last domain of the enzyme to be structurally resolved. The structure was solved in both the absence and presence of the ligand NADP(+), identifying important protein interactions with the NADPH 2'-phosphate that helps to dictate specificity for NADPH...

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Source

Identifiers

PMID: 22356131
DOI: 10.1111/j.1742-4658.2012.08544.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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